Endocrine Abstracts

Endocan has been reported as specific of endothelial tumor cells and was shown to be expressed by tip cells during angiogenesis process.The principal aims of the study are the assessment of immunohistochemical VEGF and Endocan expression in functioning and non functioning pNETs and the comparison of these markers with clinical features, Ki67 and TNM staging.We collected a total number of 79 pNETs surgical specimens for immunohistoc...

Adult growth hormone deficiency (GHD), a condition characterized by increased oxidative stress (OS), is related to augmented cardiovascular, metabolic and oncological risk. Thymidine-glycol (ThyG) (5, 6-dihydro-5, 6-dihydroxy-2’-deoxythymidine) is a marker of DNA oxidation produced when thymidine is damaged by hydroxyl radicals. It is considered a specific marker since it is not incorporated in RNA; while 8-OH-deoxyguanosine, a well-known marker of oxidative damage, is ra...